The formula was published in the "Tai Ping Imperical Grace Formulary" in 992CE.
There are many variations of the formula proportions. Each maker of Chinese patent medicine changes the proportions of the herbs slightly. The proportions in the Japanese kampo formula are , however. Some herbs may be changed also. For example, may be replaced with .
The formula was also changed slightly when it was borrowed as a Japanese kampo formula. Some species of herbs were replaced with herbs found in Japan. For example, was replaced with .